Urine drug testing is the most frequently used drug testing method and is trusted by government agencies and businesses to be accurate and scientifically sound for detecting a wide range of illicit and prescription drugs. It is the only specimen type approved for U.S. Department of Transportation (DOT) federally-regulated drug testing. While it is the most common specimen type, urine testing is not always foolproof.
In an effort to pass a drug test, donors may attempt to use common household products like vinegar, ammonia, detoxifiers, chemical additives, bleach, or other substances which may prevent a urine drug screen from detecting drugs. In addition, a donor may even substitute his/her urine with synthetic urine or beverages. As such, laboratories perform specimen validity testing (SVT) in order to determine if the specimen has abnormal chemical or physical properties and is otherwise consistent with normal human urine.